Skin

Oncology / Haematology

A RANDOMIZED PHASE III STUDY OF DURATION OF ANTI-PD-1 THERAPY IN METASTATIC MELANOMA

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Lung

Oncology / Haematology

A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Pembrolizumab (MK-3475) in Combination with Concurrent Chemoradiation Therapy Followed by Pembrolizumab with or without Olaparib (MK-7339), Compared to Concurrent Chemoradiation Therapy Alone in Participants with Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC)

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Pancreas Cancer

Oncology / Haematology

Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Early Stage Pancreatic Cancer: A Multicentre Randomised Study. (Trial Phase 2/3)

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Colorectal Cancer

Oncology / Haematology

Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Locally Advanced Rectal Cancer: A Multicentre Randomised Study (DYNAMIC-RECTAL). Randomised multi-centre biomarker-driven adjuvant treatment study. (Trial Phase 2/3)

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Colorectal Cancer

Oncology / Haematology

Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Stage III Colon Cancer: A Multicentre Phase II/III Randomised Controlled Study. (Trial Phase 2/3)

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Colorectal Cancer

Oncology / Haematology

A randomized, multicenter, parallel-group, Phase III study to compare the efficacy of arfolitixorin versus leucovorin in combination with 5 fluorouracil, oxaliplatin, and bevacizumab in patients with advanced colorectal cancer

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Colorectal Cancer

Oncology / Haematology

A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of Olaparib Alone or in Combination With Bevacizumab Compared to Bevacizumab with 5-FU in Participants with Unresectable or Metastatic Colorectal Cancer who Have Not Progressed Following First-line Induction of FOLFOX With Bevacizumab

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Advanced Solid Tumours

Oncology / Haematology

A Phase I, Open-Label, Multi-Center, Dose Escalation and Expansion Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of IMP4297 in Combination with Temozolomide in Patients with Advanced Solid Tumors and Small Cell Lung Cancer

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Prostate Cancer

Oncology / Haematology

A Phase 3, Randomized, Open-Label, Controlled Study of Cabozantinib (XL184) in Combination with Atezolizumab vs. Second Novel Hormonal Therapy (NHT) in Patients with High Risk, Metastatic Castration-Resistant Prostate Cancer

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4

Urothelial Cancer

Oncology / Haematology

A Phase 3 Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Subjects with Advanced Urothelial Cancer and Selected FGFR Gene Aberrations

Trial Phase

Non-drug Phase 1 Phase 2 Phase 3 Phase 4