Renal
Oncology / Haematology
An Open-label, Randomized, Phase 3 Study of MK-6482 in Combination with Lenvatinib (MK-7902) vs Cabozantinib for Second-line Treatment in Participants with Advanced Renal Cell Carcinoma Who Have Progressed After 1 Prior Anti-PD-1/L1 Combination Regimen
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Lung
Oncology / Haematology
A Phase 2 Randomized Double-blind Study of Relatlimab plus Nivolumab in Combination with Chemotherapy vs. Nivolumab in Combination with Chemotherapy as First Line Treatment for Participants with Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Breast
Oncology / Haematology
A Phase 3 Trial of Pembrolizumab plus Chemotherapy vs Placebo plus Chemotherapy for Chemotherapy-Candidate HR+/HER2- Metastatic Breast Cancer
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Skin
Oncology / Haematology
A RANDOMIZED PHASE III STUDY OF DURATION OF ANTI-PD-1 THERAPY IN METASTATIC MELANOMA
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Lung
Oncology / Haematology
A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Pembrolizumab (MK-3475) in Combination with Concurrent Chemoradiation Therapy Followed by Pembrolizumab with or without Olaparib (MK-7339), Compared to Concurrent Chemoradiation Therapy Alone in Participants with Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC)
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Pancreas Cancer
Oncology / Haematology
Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Early Stage Pancreatic Cancer: A Multicentre Randomised Study. (Trial Phase 2/3)
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Colorectal Cancer
Oncology / Haematology
Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Locally Advanced Rectal Cancer: A Multicentre Randomised Study (DYNAMIC-RECTAL). Randomised multi-centre biomarker-driven adjuvant treatment study. (Trial Phase 2/3)
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Colorectal Cancer
Oncology / Haematology
Circulating Tumour DNA Analysis Informing Adjuvant Chemotherapy in Stage III Colon Cancer: A Multicentre Phase II/III Randomised Controlled Study. (Trial Phase 2/3)
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Colorectal Cancer
Oncology / Haematology
A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of Olaparib Alone or in Combination With Bevacizumab Compared to Bevacizumab with 5-FU in Participants with Unresectable or Metastatic Colorectal Cancer who Have Not Progressed Following First-line Induction of FOLFOX With Bevacizumab
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4
Advanced Solid Tumours
Oncology / Haematology
A Phase I, Open-Label, Multi-Center, Dose Escalation and Expansion Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of IMP4297 in Combination with Temozolomide in Patients with Advanced Solid Tumors and Small Cell Lung Cancer
Trial Phase
Non-drug Phase 1 Phase 2 Phase 3 Phase 4